The COVID-19 epidemic has wreaked mayhem globally, bringing about considerable loss-of-life, health as well as economic costs. The roll out from the vaccination strategy has provided some light at the end of the tunnel and because the immunization strategy expands, economies around the world are beginning to open up. The ending of lockdowns will not be without its challenges and there are increases in cases when different places ease restrictions. The immunization program has lessened the risks for the seriousness of the infection as well as lessened the risk of hospitalization and death with people who are vaccinated. Infections are nevertheless coming about in the vaccinated, however the great majority as well as the more serious ones have been in individuals who are not immunized. The medical system has got far better at dealing with individuals with a coronovirus infection because the knowledge for the condition improves and a lot more treatment options are investigated. Various treatment methods have different amounts of evidence which support the approaches and there have been numerous false starts with what appear like encouraging treatments are not able to provide the benefits which were envisioned. A considerable amount of misinformation and poor science additionally supports the treatment claims for COVID-19. There will be the need for a lot more ultimate treatments and directions. The advantages of clinicians to have much more methods and therapies are urgently needed to fight the COVID-19 outbreak. Quite a few medicines are in clinical trials.